It’s a big day for every dweeb who’s ever waited five hours in line for a new iPhone: Apple’s developer conference kicks off today. The annual affair is weightier than usual, starting with a keynote that’ll measure the company’s standing in the AI arms race. Stakes are high — or at least as high as they can be for a behemoth worth ~$3T.
In today’s email:
Cryonics: A new startup working on the old goal of immortality.
Not necessary: Just $400 for your very own red pineapple.
Digits: Cruise ship economics, latte prices, and other newsy numbers.
Around the web: Secrets of a YouTube sensation, the “porcupine dilemma,” and more.
👇 Listen: Inside the winning audience experience at the Las Vegas Sphere.
The Big Idea
A startup so cool it could wake the dead
A new cryonics startup wants to make death a thing of the past.
2024-06-10T00:00:00Z
Sara Friedman
A child science prodigy building long-term hibernation pods to freeze bodies and thaw them hundreds of years later sounds like a sci-fi movie we’ve already watched.
But, it turns out, it’s becoming very real. Cradle Healthcare Co., founded by Laura Deming — who got her start in lab research at age 12 — and Hunter Davis, is looking to finally crack cryonics, perBloomberg.
Cradle says it’s creating a “pause button for biology” with a focus on three medical use cases:
Neuroscientists often use rodent brain tissue samples for research since human samples can be difficult to find. Cryopreserving slices of human brain tissue would allow researchers to order a sample at any time.
Organ donation is a highly time-sensitive process that makes testing and matching organs and donors difficult. Freezing donated organs would remove time constraints.
Many patients die from diseases that don’t yet have cures. Cryonics could preserve a patient’s body and unthaw it once a cure to their disease was discovered to treat them.
The startup, after running quietly for the last three years, emerges from stealth mode today having already raised $48m in funding.
Cool stuff
As Deming points out, cryopreserving living tissue is a technology that already exists, used for in vitro fertilization and in a recent University of Minnesota study that cryopreserved rat kidneys.
Cradle is looking to make the tricky jump into applying that science to bigger, human organs and, ultimately, whole bodies.
For now, it’s focusing on rodent brain slices, and has successfully cooled and rewarmed a sample while retaining the neurons’ electrical activity.
Of course, there are obstacles: Ice crystals from freezing can ruin cells and cryoprotectants that protect from crystallization are toxic.
And Cradle isn’t the first company to attempt to advance cryonics: Alcor Life Extension Foundation famously has 200+ bodies and heads — and some pets — frozen in its headquarters.
The only problem? No one has been revived… yet.
Free Resource
ChatGPT hacks for business professionals
Ballers everywhere are breaking into AI by finding ways to use it at work, and you should, too.
Take our ebook of 100 ChatGPT hacks you can use across sales, marketing, management, and customer support.
Your personal problem-solver:
ChatGPT use cases
Ideas for improving your workflow
Best practices for asking questions
100 ways to try ChatGPT today
You’re either riding the wave or waiting for rain, and we wouldn’t recommend the latter.
Tesla’s done its special-release branded alcohol thing again — this time selling a $450 lightning-shaped bottle of mezcal. Now if the automaker can just sell ~124.4m bottles, it’ll cover Elon Musk’s proposed $56B pay package, which shareholders will vote on this Thursday.
SNIPPETS
The US added 272k new jobs in May, beating estimates. The unemployment rate also rose from 3.9% to 4% — the highest level in two years.
Also up in America: The countrygained 600k new millionaires in 2023, a 7.3% YoY increase, according to a new Capgemini study. Today’s 7.5m American millionaires have a combined fortune of $26.1T.
Google’s AI Overviews will be telling fewer people to eat rocks and put glue on their pizza — for now. One analysis shows the search-upending new tech rolled out on 84% of queries last month, but is now only appearing on ~15% of results.
TJX, which operates TJ Maxx, HomeGoods, and Marshalls, said it will start using body cameras for some employees in its retail stores to prevent theft.
Ikea is hiring 10 people at $17/hour to work at “The Co-worker Game,” a virtual Roblox store where users can browse furniture and experience what working at Ikea would be like.
New Yorkpassed a bill making it illegal for people to snap up and resell hot restaurant reservations. The bill, lauded by OpenTable and Resy CEOs, awaits the governor’s sign-off.
No nuts? A New York woman is suing Cold Stone Creamery after learning that its pistachio ice cream contains no pistachios, adding to a trend in lawsuits against alleged false advertising in food.
Whatcha gonna do? Go see Bad Boys 4, apparently. The Will Smith flick became the first summer debut to outperform box office expectations, making $56m in the US and $104.6m globally.
Luxury dog airline Bark Air has been ferrying fluffballs for just over two weeks, but it’s already facing its first lawsuit, for allegedly misusing an airport terminal.
Don't miss this...
Jennifer Romolini had what she thought was the dream: a C-suite tech job, speaking gigs, and a hit book. So why did it suck so much? She joined our podcast to talk about workaholism, toxic girl-boss culture, and more.
Not Necessary
Fresh Del Monte
Do you like pina coladas and getting caught in the rain? How about losing ~$400? That one doesn’t sound as fun, we know. But that’s the price you have to cough up if you want to get your hands on a Del Monte Rubyglow pineapple. The special red fruit took 16 years to develop in Costa Rica and was made by crossing a traditional pineapple with a Morada pineapple, which is usually inedible. You can scoop up a Rubyglow in its speciality gift box for $396 through California grocer Melissa’s Produce.
Fit the bill
There are thousands of companies valued at $1B+. How many clues do you need to identify today’s billion-dollar brand?
Clue 1: In the 1940s, its products included Soilax “A,” Soilax “B,” Soilax “C,” Super Soilax, Electrosol, Tetrox, Pan Dandy, Mikro-Klene, and Glass Magic. You may have guessed, but cleaning is a central purpose of this company.
Clue 2: This company’s biggest acquisition was its 2011 purchase of Nalco for $5.4B. The wholly owned subsidiary makes industrial water-treatment products like Corexit, a dispersant used during oil spills.
Clue 3: Your life may depend on this company doing a good job — it leads the efforts to keep operating rooms and medical tools sterile in 8.7k+ hospitals.
👇 Scroll to the bottom for the answer 👇
By the Numbers
Digits: Owls down the aisles, cruise economics, and other newsy numbers
Half of downtown Juneau, Alaska, is in danger, owls at weddings, and more.
2024-06-10T00:00:00Z
Juliet Bennett Rylah
$1,727: Total revenue per passenger on a Carnival cruise, including tickets — which average $1,125 per passenger — and excursions, food, drinks, games, and other amenities. That may sound steep, but when factoring in the costs of operating a cruise and the deprecation of Carnival’s fleet over each ship’s 30-year tenure, ~$150 is left — a 9% margin that’s lower than the 15%-16% margins the company often enjoyed pre-pandemic.
$951:How much one UK couple paid to have seven birds, including a ring-bearing owl, attend their wedding. Owls have become an increasingly popular wedding trend across the UK over the past decade, thanks in part to their use as couriers in the Harry Potter world. This typically goes well; however, sometimes an owl does fly off with the rings and, in one case, attacked a wedding guest in Cheshire, England.
550:Buildings at moderate to severe landslide or avalanche risk in Juneau, Alaska, accounting for about half of downtown. Climate change has led to wetter weather, exacerbating the issue in an area prone to such disasters. In Juneau, there are 52 potential avalanche paths, any of which could see buildings swept away at 55 mph. Yet, per The Lever, residents and lawmakers are grappling with a solution hampered by bureaucracy and red tape — like what will happen with property values and insurance.
$5.14: Average cost of cold brew at US coffee shops, per Toast data. A regular cup of Joe came in at $3.08, while a latte was $5.46 — still not nearly enough that abstaining from them would net you a down payment on a house. If you’re looking for the cheapest coffee, you’ll find it in Nebraska for $2.12, 31% lower than average. And interestingly, tea (average price: $3.74) was a more popular purchase in 30 states.
AROUND THE WEB
📅 On this day: In 1935, recovering alcoholics Bill Wilson and Dr. Robert Smith founded Alcoholics Anonymous in Akron, Ohio.
🧠 How to: learn from the porcupine dilemma — the human desire to be both close and distant from others.
🎧 Marketing Against the Grain: Take notes from 19-year-old sensation Jenny Hoyos, who gives the ultimate master class on cracking the code on YouTube.